Publications

Questions? Contact us at info@nkartatx.com

Presentations & Posters


Nkarta Therapeutics Corporate Presentation
Presentation | July 2020


A combination of CAR-NK and CAR-T cells results in rapid and persistent anti-tumor efficacy while reducing CAR-T cell mediated cytokine release and T-cell proliferation
Poster Presentation | AACR | June 2020


CRISPR-Cas9-gRNA RNP mediated gene knockout of TGFbR2 and CISH enhances CD19-CAR NK cell function and provides resistance to TGFb
Poster Presentation | AACR | June 2020


Co-expression of a CD19-OX40-CD3ζ CAR with membrane bound IL-15 enhances natural killer cell function
Poster Presentation | AACR | November 2019


Stimulatory cells plus IL-12 and IL-18 augments NK cell expansion, transduction, memory phenotype, and in vitro and in vivo CAR NK cytotoxicity & persistence
Poster Presentation | SITC | November 2019


Expanded and engineered NK cells for the treatment of hepatocellular carcinoma
Poster Presentation | AACR | July 2019


Expanded and engineered NK cells upregulate expression of activation and survival genes associated with increased cytotoxicity and persistence
Poster Presentation | AACR | March 2019


NK Cells Engineered to Express a Bispecific CD123/NKG2D Chimeric Antigen Receptor (CAR) and IL-15 As Off-the-Shelf Therapy for Acute Myeloid Leukemia
Poster Presentation | Keystone | March 2019


Co-expression of a chimeric NKG2D receptor with membrane bound IL-15 enhances natural killer cell function and long term persistence in vitro and in vivo
Poster Presentation | SITC | March 2018


Publications & References


Natural Killer Cells May Be Scaled and Engineered as a Next Generation, Off-the-Shelf Cell Therapy for Cancer
Cell & Gene Therapy Insights, Trager, October 2019


The Rise of Allogeneic Natural Killer Cells As a Platform for Cancer Immunotherapy: Recent Innovations and Future Developments
Front Immunol, Veluchamy et al, May 2017


Expanded and Activated Natural Killer Cells for Immunotherapy of Hepatocellular Carcinoma
Cancer Immunol Res , Kamiya, Chang, Campana, July 2016


Ex Vivo-Expanded Natural Killer Cells Demonstrate Robust Proliferation in Vivo in High-Risk Relapsed Multiple Myeloma Patients
J Immunother, Szmania et al, January 2015


Autonomous Growth and Increased Cytotoxicity of Natural Killer Cells Expressing Membrane-Bound interleukin-15
Blood, Imamura et al, August 2014


Clearance of Acute Myeloid Leukemia by Haploidentical Natural Killer Cells Is Improved Using IL-2 Diphtheria Toxin Fusion Protein
Blood, Bachanova et al, June 2014


A Chimeric Receptor With NKG2D Specificity Enhances Natural Killer Cell Activation and Killing of Tumor Cells
Cancer Res, Chang et al, March 2013


Natural Killer Cell Reprogramming With Chimeric Immune Receptors
Methods Mol Biol, Shimasaki, Campana, 2013


Cytotoxicity of Activated Natural Killer Cells Against Pediatric Solid Tumors
Clin Cancer Res, Cho et al, August 2010


Genetic modification of primary natural killer cells overcomes inhibitory signals and induces specific killing of leukemic cells
Blood, Imai, Iwamoto, Campana, March 2008